Regenerative medicine for the treatment of heart disease
- An effective tool for drug screening in heart disease models
- Regenerative medicine for the treatment of heart disease
- A potential biological patch for post-infarct scars
- A new technology for the generation of mature human cardiomyocytes
One application for this technology is the in vitro use of a cardiac construct for the screening or evaluation of compounds for cardioprotective or cardiotoxic properties, and for cardiac disease modeling.
The present invention also represents a new therapeutic option for patients with acute myocardial infarction, which present post-infarct scars. CTE products could be implanted in damaged myocardium and shrink simultaneously with healthy tissue. At that moment, an improvement in contractile strength would occur, as well as in patient’s life quality and life expectancy