• Clinical evaluation of the efficacy of new drugs and new treatment approaches for gliomas and meningiomas (Jordi Bruna, Miguel Gil, Ana Lucas, Miquel Macià, Carles Majós)
    • Chemotherapy-induced peripheral neuropathies (Jordi Bruna, Roser Velasco)
    • Cancer and cognition (Marta Simó)
    • Leptomeningeal metastases (Jordi Bruna, Miguel Gil)
    • Survival prognostic factors involved in central nervous system tumours (Noemí Vidal, Jordi Bruna, Carles Majós)
    • Prevention and personalised treatment of brain metastases: development of new therapies based on the prevention and prognosis of biomarkers (Miguel Gil, Noemí Vidal, Gerard Plans, Ana Lucas)

Seizure-Susceptible brain regions in glioblastoma: identification of patients at risk.

Cayuela N, Simó M, Majós C, Rifà-Ros X, Gállego Pérez-Larraya J, Ripollés P, Vidal N, Miró J, Gil F, Gil-Gil M, Plans G, Graus F, Bruna J

EUROPEAN JOURNAL OF NEUROLOGY (ISSN/ISBN: 13515101)

2018

Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics

Izquierdo C., Alentorn A., Idbaih A., Simó M., Kaloshi G., Ricard D., Barritault M., Meyronet D., Bruna J., Honnorat J., Delattre J., Ducray F.

JOURNAL OF NEURO-ONCOLOGY (ISSN/ISBN: 0167594X). 136 (3) : 533-539

2018

Sigma-1 receptor: a new player in neuroprotection against chemotherapy-induced peripheral neuropathy.

Bruna J, Velasco R

NEURAL REGENERATION RESEARCH (ISSN/ISBN: 16735374). 13 (5) : 775-778

2018

Corrigendum

Cayuela N; Jaramillo-Jiménez E; Majos C; Velasco R; Boget T; Graus F; Bruna J; Simo M

NEURO-ONCOLOGY. (ISSN/ISBN: 15228517).

2018

Radiological Characteristics and Natural History of Adult IDH-Wildtype Astrocytomas with TERT Promoter Mutations

Izquierdo C; Barritault M; Poncet D; Cartalat S; Joubert B; Bruna J; Jouanneau E; Guyotat J; Vasiljevic A; Fenouil T; Berthezène Y; Honnorat J; Meyronet D; Ducray F

NEUROSURGERY. (ISSN/ISBN: 0148396X).

2018

Rechallenge with oxaliplatin and peripheral neuropathy in colorectal cancer patients

Martinez-Villacampa, M.; Tavera, S. Besora; Vivas, C. Santos; Izquierdo, C.; Bruna, J.; Velasco, R.

ANNALS OF ONCOLOGY. (ISSN/ISBN: 09237534). 29

2018

Rechallenge with oxaliplatin and peripheral neuropathy in colorectal cancer patients.

Besora S; Santos C; Izquierdo C; Martinez-Villacampa MM; Bruna J; Velasco R

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. (ISSN/ISBN: 01715216).

2018

Inconclusive evidence to support the use of minimally-invasive radiofrequency denervation against chronic low back pain

Argyriou, Andreas A.; Anastopoulou, Garifallia G.; Bruna, Jordi;

ANNALS OF TRANSLATIONAL MEDICINE (ISSN/ISBN: 2305-5839). 6 (7) : ARTN 127

2018

Syndrome and outcome of antibody-negative limbic encephalitis.

Graus F, Escudero D, Oleaga L, Bruna J, Villarejo-Galende A, Ballabriga J, Barceló MI, Gilo F, Popkirov S, Stourac P, Dalmau J

EUROPEAN JOURNAL OF NEUROLOGY (ISSN/ISBN: 13515101)

2018

Risk stratification of oxaliplatin induced peripheral neurotoxicity applying electrophysiological testing of dorsal sural nerve

Alberti P., Rossi E., Argyriou A., Kalofonos H., Briani C., Cacciavillani M., Campagnolo M., Bruna J., Velasco R., Cazzaniga M., Cortinovis D., Valsecchi M., Cavaletti G.

SUPPORTIVE CARE IN CANCER (ISSN/ISBN: 09414355). 1-9

2018

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CONTRATOS PARA LA INTENSIFICACION DE LA ACTIVIDAD INVESTIGADORA EN EL SNS

Bruna Escuer, Jordi (Investigador principal (IP))

Ref.: INT16/00219

Entitat finançadora:
  • FIS-INSTITUTO DE SALUD CARLOS III

2017-01-01 - 2017-04-07

Toxicitat cognitiva induïda per la quimioteràpia en pacients amb càncer de pulmó

Simo Parra, Marta (Participante)

CONTRATOS JUAN RODES

Simo Parra, Marta (Investigador principal (IP))

Ref.: JR15/00027

Entitat finançadora:
  • FIS-INSTITUTO DE SALUD CARLOS III

2016-01-04 - 2019-01-03

Estudio exploratorio sobre la etiopatogenia, biomarcadores de riesgo y mecanismos implicados en la regeneración de la neuropatía inducida por platinos

Bruna Escuer, Jordi (Investigador principal (IP))

Ref.: PI15/01303

Entitat finançadora:
  • FIS-INSTITUTO DE SALUD CARLOS III

2016-01-01 - 2018-12-31

An observational retrosepctive cohort study to evaluate the progression-free survival and overall survival at patients who participated in the SIGM-202 clinical trial

Simo Parra, Marta (Participante)

Entitat finançadora:
  • LABORATORIOS DR. ESTEVE, S.A.

Posible utilidad de la resonancia magnética preradioterapia precos (PRMR) para el seguimiento de los gliomas de alto grado

MAJOS TORRO, CARLOS (Investigador principal (IP))

Ref.: PR309/12

Entitat finançadora:
  • GEINO

2013-04-01 - 2016-03-31

Neurocognitive function sub-study of BO21990: A randomized, double blind, placebo controlled, multicenter Phase III trial of bevacizumab, temozolomide and radiotherapy, followed by bevacizumab and temozolomide versus placebo, temozolomide and radiotherapy followed by placebo and temozolomide in patients with newly diagnosed glioblastoma

Simo Parra, Marta (Investigador/a)

Entitat finançadora:
  • ROCHE FARMA, S.A.

A Randomized, Double-Blind, Phase 2, Dose-Ranging Study to Evaluate the Safety and Efficacy of Veliparib and Whole Brain Radiation Therapy Versus Placebo and Whole Brain Radiation Therapy in Subjects With Brain Metastases From Non-Small Cell Lung Cancer. NCT01657799

Simo Parra, Marta (Investigador/a)

Entitat finançadora:
  • ABBOTT CIENTÍFICA, S.A.

Ensayo prospectivo multicéntrico de NovoTTF-100A en combinación con temozolomida comparado con temozolomida en monoterapia en pacientes con GBM de reciente diagnóstico

Simo Parra, Marta (Investigador/a)

Entitat finançadora:
  • NOVOCURE LTD

CONTRATOS POST FSE RIO HORTEGA

Simo Parra, Marta (Investigador principal (IP))

Ref.: CM11/00256

Entitat finançadora:
  • FIS-INSTITUTO DE SALUD CARLOS III

2012-01-24 - 2014-01-23

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METHOD FOR DETERMINING THE RISK OF DEVELOPING BRAIN METASTASIS, AND A KIT TO CARRY OUT SAID METHOD

SANZ PAMPLONA, Rebeca ; SIERRA JIMENEZ, Angels ; OLIVA MIGUEL, Baldomero ; MORENO AGUADO, Victor Raul ; GIL GIL, Juan Miguel

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  • Identification of markers of clinical and neurophysiological predictive risk for developing oxaliplatin-induced neuropathy.
  • New demonstrations on the efficacy of the new sigma-1 receptor antagonist in preventing acute oxaliplatin-induced neuropathy in a randomised, phase 2 study.
  • Documentation of longitudinal brain changes associated with prophylactic cranial irradiation and chemotherapy in patients with small-cell lung cancer.
  • Identification of a common feature in glioblastomas: intrinsic deficiency of the DFF40/CAD endonuclease which affects DNA hydrolysis during caspase-dependent cell death.