• Characterisation of the genomic and functional structure of the codifying pfkfb3 and pfkfb4 genes for 6-phosphofructo-2- kinase/fructose 2,6-bisphosphatase
  • Study of the function of AMP kinase in diabetic animal models and cell preconditioning
  • Study of gluconeogenesis in diabetic animal models
  • Study of the inherent complications of extracorporeal circulation
  • Study of the influence of different ergogenic aids on physical performance
  • Evaluation of the influence of acute fat intake, prior to exercise, on the adaptation to effort and the performance in long-lasting efforts
  • Study of the role of PEPCK-M in cancer metabolism
  • Metabolic reprogramming in obesity and type-2 diabetes

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

Schneider T., Martinez-Martinez A., Cubillos-Rojas M., Bartrons R., Ventura F., Rosa J.

ONCOTARGET. (ISSN/ISBN: 19492553). 9(59): 31531-31548

2018

Regional grey matter volume correlates of gambling disorder, gambling-related cognitive distortions, and emotion-driven impulsivity

Ruiz de Lara C., Navas J., Soriano-Mas C., Sescousse G., Perales J.

INTERNATIONAL GAMBLING STUDIES (ISSN/ISBN: 14459795). 1-22

2018

PI3K-Akt signaling controls PFKFB3 expression during human T-lymphocyte activation.

Simon-Molas H, Arnedo-Pac C, Fontova P, Vidal-Alabró A, Castaño E, Rodríguez-García A, Navarro-Sabaté À, Lloberas N, Manzano A, Bartrons R

MOLECULAR AND CELLULAR BIOCHEMISTRY (ISSN/ISBN: 03008177)

2018

Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism

Soukupova J., Malfettone A., Hyroššová P., Hernández-Alvarez M., Peñuelas-Haro I., Bertran E., Junza A., Capellades J., Giannelli G., Yanes O., Zorzano A., Perales J., Fabregat I.

SCIENTIFIC REPORTS (ISSN/ISBN: 20452322). 7 (1)

2017

The role of affect-driven impulsivity in gambling cognitions: A convenience-sample study with a Spanish version of the Gambling-Related Cognitions Scale

Del Prete, Francesco; Steward, Trevor; Navas, Juan F.; Fernandez-Aranda, Fernando; Jimenez-Murcia, Susana; Oei, Tian P. S.; Perales, Jose C.;

JOURNAL OF BEHAVIORAL ADDICTIONS (ISSN/ISBN: 20625871). 6 (1) : 51-63

2017

TGF-beta 1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

Rodriguez-Garcia, Ana; Samso, Paula; Fontova, Pere; Simon-Molas, Helga; Manzano, Anna; Castano, Esther; Luis Rosa, Jose; Martinez-Outshoorn, Ubaldo; Ventura, Francesc; Navarro-Sabate, Aurea; Bartrons, Ramon;

FEBS JOURNAL (ISSN/ISBN: 17424658). 284 (20) : 3437-3454

2017

Trait and neurobiological underpinnings of negative emotion regulation in gambling disorder.

Navas JF, Contreras-Rodríguez O, Verdejo-Román J, Perandrés-Gómez A, Albein-Urios N, Verdejo-García A, Perales JC

ADDICTION (ISSN/ISBN: 09652140). 112 (6) : 1086-1094

2017

Delay discounting and impulsivity traits in young and older gambling disorder patients.

Steward T, Mestre-Bach G, Fernández-Aranda F, Granero R, Perales JC, Navas JF, Soriano-Mas C, Baño M, Fernández-Formoso JA, Martín-Romera V, Menchón JM, Jiménez-Murcia S

ADDICTIVE BEHAVIORS (ISSN/ISBN: 03064603). 71 : 96-103

2017

PEPCK-C reexpression in the liver counters neonatal hypoglycemia in Pck1(del/del) mice, unmasking role in non-gluconeogenic tissues

Semakova, Jana; Hyrossova, Petra; Mendez-Lucas, Andres; Cutz, Ernest; Bermudez, Jordi; Burgess, Shawn; Alcantara, Soledad; Perales, Jose C.;

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (ISSN/ISBN: 11387548). 73 (1) : 89-98

2017

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.

Cubillos-Rojas M; Schneider T; Bartrons R; Ventura F; Rosa JL

ONCOTARGET (ISSN/ISBN: 19492553). 8 (37) : 61824-61836

2017

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Estudio integrativo y traslacional de la desregulación metabólica debida a la obesidad.Repercusiones sobre la plasticidad del tejido adiposo blanco

Garcia-Roves Gonzalez, Pablo Miguel (Investigador principal (IP))

Ref.: PI15/00701

Entitat finançadora:
  • FIS-INSTITUTO DE SALUD CARLOS III

2016-01-01 - 2018-12-31

ESTANCIA BREVE BECA FPI BES-2007-16437

Bartrons Bach, Ramon (Investigador principal (IP))

Ref.: EEBB-2011-44136

Entitat finançadora:
  • MINISTERIO DE EDUCACIÓN Y CIENCIA

2011-01-01 - 2011-12-31

Regulación y función de los genes pfkfb3,pfkfb4 y TIGAR

Bartrons Bach, Ramon (Investigador principal (IP))

Ref.: BUF2009-07380

Entitat finançadora:
  • MINISTERIO DE EDUCACIÓN Y CIENCIA

2010-01-01 - 2012-12-31

FPI - BES-2007-16437

Bartrons Bach, Ramon (Investigador principal (IP))

Ref.: FPI-BES-2007-16437

Entitat finançadora:
  • MINISTERIO DE EDUCACIÓN Y CIENCIA

2009-07-02 - 2011-07-01

Conv. Mutua Madrileña -- DR. JAVIERRE

Javierre Garces, Casimiro (Investigador principal (IP))

Ref.: 07PRV009

Entitat finançadora:
  • FUNDACIÓ MUTUA MADRILEÑA

2007-05-04 - 2010-05-03

BFU2006-02412

Bartrons Bach, Ramon (Investigador principal (IP))

Ref.: BFU2006-02412

Entitat finançadora:
  • MINISTERIO DE EDUCACIÓN Y CIENCIA

2007-01-01 - 2009-09-30

Inv. Efectes aspirina -- Dr. Bartrons

Bartrons Bach, Ramon (Investigador principal (IP))

Ref.: 94VAR026

MTV3

Bartrons Bach, Ramon (Investigador principal (IP))

Ref.: MTV3

Entitat finançadora:
  • MARATO TV3

2006-01-01 - 2009-12-31

NOVES ESTRATÈGIES DE TERAPIA GÈNICA PER AL TRACTAMENT DE LA MALALTIA INFLAMATORIA INTESTINAL: LA SILENCIACIÓ DE L´EXPRESSIÓ DE TNFalfa I LA SOBREEXPRESSIÓ D´INTERLEUQUINA-10

Perales Losa, Jose Carlos (Investigador principal (IP))

Ref.: 31633

2006-01-01 - 2009-12-31

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Estudio de la fosfoenolpiruvato carboxiquinasa mitocondrial (PEPCK-M) en la función mitocondrial y la homeostasis de la glucosa

Perales Losa, Jose Carlos (Director) Doctorando: Andrés Méndez Lucas

2012

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