• To identify new therapeutic strategies and mechanisms of resistance to current treatments for breast cancer

• To evaluate the role of the RANK signalling pathway in epithelial homeostasis, inflammation and cancer, and its potential as a therapeutic target.

RANK Induces Epithelial-Mesenchymal Transition and Stemness in Human Mammary Epithelial Cells and Promotes Tumorigenesis and Metastasis

Palafox, Marta; Ferrer, Irene; Pellegrini, Pasquale; Vila, Sergi; Hernandez-Ortega, Sara; Urruticoechea, Ander; Climent, Fina; Teresa Soler, Maria; Munoz, Purificacion; Vinals, Francesc; Tometsko, Mark; Branstetter, Dan; Dougall, William C.; Gonzalez-Suarez, Eva;

CANCER RESEARCH (ISSN/ISBN: 00085472). 72 (11) : 2879-2888

2012

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AYUDAS JUAN DE LA CIERVA - INCORPORACION 2017

Gonzalez Suarez, Eva (Investigador principal (IP))

Entitat finançadora:
  • MINISTERIO DE EDUCACIÓN Y CIENCIA

2018-12-05 - 2020-12-04

CONTRACTES D'INCORPORACIÓ DE CIENTÍFICS I TECNÒLEGS ALS GRUPS DE RECERCA

Gonzalez Suarez, Eva (Investigador principal (IP))

2018-02-27 - 2020-12-31

Coordinator of an Investigator Initiated Clinical Trial: An open label biomarker pilot study of the antitumoral activity of denosumab in the pre- operative setting of early breast cancer

Gonzalez Suarez, Eva (Coordinador del proyecto total, red o consorcio)

Entitat finançadora:
  • AMGEN INC

SAF2017-86117-R. New insights in RANK signaling pathway: from biology to treatment

Gonzalez Suarez, Eva (Participante)

Entitat finançadora:
  • MINISTRY OF ECONOMY AND FINANCE

2018-01-01 - 2021-01-01

Sara Borrell postdoctoral contract. CD17/00223.

Gonzalez Suarez, Eva (Participante)

Entitat finançadora:
  • INSTITUTO DE SALUD CARLOS III

2018-01-01 - 2021-01-01

Nuevas dianas terapéuticas en cáncer epitelial New therapeutic targets in epithelial tumors

Gonzalez Suarez, Eva (Investigador principal (IP))

Entitat finançadora:
  • AGAUR-GENERAL.CATALUNYA

2018-01-01 - 2020-12-31

Nuevos avances en el estudio de la vía de RANK en cáncer de mama: de la biología al tratamiento

Gonzalez Suarez, Eva (Investigador principal (IP))

Entitat finançadora:
  • MINISTERIO DE EDUCACIÓN Y CIENCIA

2018-01-01 - 2020-12-31

PERIS FP technician SLT006/17/00122

Gonzalez Suarez, Eva (Participante)

Entitat finançadora:
  • GENERALITAT DE CATALUNYA

2018-01-01 - 2021-01-01

WOMEN’S CANCER

Gonzalez Suarez, Eva (Investigador principal (IP))

Ref.: B-DEBATE

Entitat finançadora:
  • BIOCAT

2017-11-16 - 2018-11-15

An open label biomarker pilot study of the antitumoral activity of denosumab in the pre- operative setting of early breast cancer

Gonzalez Suarez, Eva (Investigador principal (IP))

Ref.: 20119112

2017-01-26 - 2019-01-26

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RANK signaling in mammary spontaneous tumorigenesis and tumor-stromal crosstalk

Gonzalez Suarez, Eva (Director) Doctorando: Guillermo Yoldi Salinas

2018

Identification of mechanisms of acquired resistance to taxanes in triple negative breast cancer using patient-derived xenografts: a step closer to clinics

Gonzalez Suarez, Eva (Director) Doctorando: Jorge Gomez Miragaya

2018

Impact of RANK overexpression on mammary stem cell fate, alveolar cell differentiation and tumorigenesis

Gonzalez Suarez, Eva (Director) Doctorando: Alejandro Cordero Casanovas

2015

Estudio de la vía de señalización de RANK y RANKL en células de mama humanas y generacion de ortoxenopacientes de cáncer de mama

Gonzalez Suarez, Eva (Director) Doctorando: Marta Palafox Sánchez

2015

DT Tesis doctoral : Estudio de la vía de señalización de RANK/RANKL en células humanas y generación de ortoxenopacientes de cáncer de mama

Gonzalez Suarez, Eva (Director) Doctorando: Marta Palafox Sánchez

2014

RANK signaling: a master regulator of mammary stemness and cancer

Gonzalez Suarez, Eva (Director) Doctorando: Pasquale Pellegrini

2014

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The group has received uninterrupted competitive funding from public and private bodies, both nationally and internationally, with a total of 17 grants. Funding agencies include the following: MINECO, ISCIII, AECC, Mutua Madrileña Foundation, Marató de TV3, as well as the most prestigious international associations (Concern Foundation (USA), Susan G. Komen Foundation (USA)). It recently received an ERC Consolidator Grant from the European Union, awarded to Dr González Suárez.

The group has also signed contacts with the industry and coordinates initial-phase clinical trials.