Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53, Independent of Increased Ribosome Content
Morcelle C, Menoyo S, Morón-Duran FD, Tauler A, Kozma SC, Thomas G, Gentilella A
2019
S6 kinase 1 plays a key role in mitochondrial morphology and cellular energy flow.
Tran Q, Jung JH, Park J, Lee H, Hong Y, Cho H, Kim M, Park S, Kwon SH, Kim SH, Thomas G, Kim KP, Cho MH
CELLULAR SIGNALLING (ISSN/ISBN: 08986568)
2018
Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR.
Veiga SR, Ge X, Mercer CA, Hernández-Álvarez MI, Thomas HE, Hernandez-Losa J, Ramón Y Cajal S, Zorzano A, Thomas G, Kozma SC
CLINICAL CANCER RESEARCH (ISSN/ISBN: 10780432)
2018
Mitochondrial Complex I Activity Is Required for Maximal Autophagy
Thomas H., Zhang Y., Stefely J., Veiga S., Thomas G., Kozma S., Mercer C.
CELL REPORTS. (ISSN/ISBN: 22111247). 24(9): 2404-2417.E8
2018
Ribosome biogenesis in cancer: New players and therapeutic avenues
Pelletier J., Thomas G., Volarevi S.
NATURE REVIEWS CANCER (ISSN/ISBN: 1474175X). 18 (1) : 51-63
2018
Phenformin-induced mitochondrial dysfunction sensitizes hepatocellular carcinoma for dual inhibition of mTOR
Veiga, S.; Ge, X.; Mercer, C.; Hernandez-Alvarez, M.; Thomas, H.; Hernandez-Losa, J.; Cajal, S. R. Y.; Zorzano, A.; Thomas, G.; Kozma, S.;
ANNALS OF ONCOLOGY. (ISSN/ISBN: 09237534). 29
2018
A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies
Wise-Draper T., Moorthy G., Salkeni M., Karim N., Thomas H., Mercer C., Beg M., O’Gara S., Olowokure O., Fathallah H., Kozma S., Thomas G., Rixe O., Desai P., Morris J.
TARGETED ONCOLOGY (ISSN/ISBN: 17762596). 12 (3) : 1-10
2017
Characterization of the pre-ribosomal complex, which mediates the p53 Impaired Ribosome Biogenesis Checkpoint (IRBC)
Menoyo, Sandra; Gentilella, Antonio; Thomas, George;
CANCER RESEARCH (ISSN/ISBN: 00085472). 77
2017
A novel 40S complex involved in the regulation of 5 ' TOP mRNA stability: A role in mTOR hyperactivated tumors?
Gentilella, Antonio; Moron-Duran, Francisco D.; Rocha, Guilherme Z.; Riano-Canalias, Ferran; Pelletier, Joffrey; Tauler, Albert; Kozma, Sara; Thomas, George;
CANCER RESEARCH (ISSN/ISBN: 00085472). 77
2017
Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo
Sesé M., Fuentes P., Esteve-Codina A., Béjar E., McGrail K., Thomas G., Aasen T., Ramón y Cajal S.
ONCOTARGET. (ISSN/ISBN: 19492553). 8(70): 114856-114876
2017
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