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Neurometabolic diseases



Research lines

- X-linked Adrenoleukodystrophy as a paradigm of neurometabolic disease


- Pathophysiology of Pelizaeus Merzbacher, Metachromatic Leukodystrophy and beyond


- Comparative insight in the peroxisomal proteome and metabolome


Selected papers (2009)

 

Fourcade S, Ruiz M, Camps C, Schluter A, Houten SM, Mooyer PA, Pàmpols T, Dacremont G, Wanders RJ, Giròs M, Pujol A. A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis. American Journal of Physiology-Endocrinology and Metabolism. 2009;296(1):E211-E21.

Liu J, Sabeva NS, Bhatnagar S, Li X, Pujol A, Graf GA. ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat. J Lipid Res. 2009 Jun 25.  

Schlüter A, Real-Chicharro A, Gabaldón T , Sánchez-Jiménez F and Pujol A*. PeroxisomeDB 2.0: an integrative view on the global peroxisomal metabolome. Nuc Acids Res, 2009 Nov 5, 1-6.

Mastroeni R, Bensadoun JC, Charvin D, Aebischer P, Pujol A, Raoul C. Insulin-like Growth Factor-1 and Neurotrophin-3 Gene Therapy Prevents Motor Decline in an X-Linked Adrenoleukodystrophy Mouse Model. Annals of Neurology. 2009;66(1):117-22.

imatge personal
 

Group leader

Aurora Pujol
Telephone  
+34 932607343
E-mail  
apujol@idibell.cat
 
© 2013 Institut d'Investigació Biomèdica de Bellvitge



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