logo IDIBELL
Català  |   Castellano  |   English
Search
The InstituteResearchWhat's onPlatformsJob offers
 

Hereditary cancer


Research lines

Study of colorectal cancer and hereditary breast cancer molecular basis


Molecular diagnosis of gastrointestinal tumors and breast cancer


Development of animal models after orthotopic implantation of tumors from patients with hereditary cancer in athymic mice


Clinical, genetic and molecular basis of Neurofibromatosis


Papers (2014-2015)

 

Bellido F, Pineda M, Sanz-Pamplona R, Navarro M, Nadal M, Lazaro C, Blanco I, Moreno V, Capella G, Valle L (2014) Comprehensive molecular characterisation of hereditary non-polyposis colorectal tumours with mismatch repair proficiency. Eur J Cancer 50: 1964-72

 

Castillejo A, Vargas G, Castillejo MI, Navarro M, Barbera VM, Gonzalez S, Hernandez-Illan E, Brunet J, Ramon y Cajal T, Balmana J, Oltra S, Iglesias S, Velasco A, Solanes A, Campos O, Sanchez Heras AB, Gallego J, Carrasco E, Gonzalez Juan D, Segura A, Chirivella I, Juan MJ, Tena I, Lazaro C, Blanco I, Pineda M, Capella G, Soto JL (2014) Prevalence of germline MUTYH mutations among Lynch-like syndrome patients. Eur J Cancer 50: 2241-50

 

Lobaton T, Azuara D, Rodriguez-Moranta F, Loayza C, Sanjuan X, de Oca J, Fernandez-Robles A, Guardiola J, Capella G (2014) Relationship between methylation and colonic inflammation in inflammatory bowel disease. World J Gastroenterol 20: 10591-8

Lopez-Doriga A, Feliubadalo L, Menendez M, Lopez-Doriga S, Moron-Duran FD, del Valle J, Tornero E, Montes E, Cuesta R, Campos O, Gomez C, Pineda M, Gonzalez S, Moreno V, Capella G, Lazaro C (2014) ICO amplicon NGS data analysis: a Web tool for variant detection in common high-risk hereditary cancer genes analyzed by amplicon GS Junior next-generation sequencing. Hum Mutat 35: 271-7

Mur P, Pineda M, Romero A, Del Valle J, Borras E, Canal A, Navarro M, Brunet J, Rueda D, Ramon YCT, Lazaro C, Caldes T, Blanco I, Soto JL, Capella G (2014) Identification of a founder EPCAM deletion in Spanish Lynch syndrome families. Clin Genet 85: 260-6

 

Pineda M, Gonzalez-Acosta M, Thompson BA, Sanchez R, Gomez C, Martinez-Lopez J, Perea J, Caldes T, Rodriguez Y, Landolfi S, Balmana J, Lazaro C, Robles L, Capella G, Rueda D (2014) Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors. Clin Genet

Segui N, Guino E, Pineda M, Navarro M, Bellido F, Lazaro C, Blanco I, Moreno V, Capella G, Valle L (2014) Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer. PLoS One 9: e86063

Segui N, Navarro M, Pineda M, Koger N, Bellido F, Gonzalez S, Campos O, Iglesias S, Valdes-Mas R, Lopez-Doriga A, Gut M, Blanco I, Lazaro C, Capella G, Puente XS, Plotz G, Valle L (2014) Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype. Gut 64: 355-6

 

Segui N, Navarro M, Pineda M, Koger N, Bellido F, Gonzalez S, Campos O, Iglesias S, Valdes-Mas R, Lopez-Doriga A, Gut M, Blanco I, Lazaro C, Capella G, Puente XS, Plotz G, Valle L (2015) Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype. Gut 64: 355-6

 

Segui N, Pineda M, Navarro M, Lazaro C, Brunet J, Infante M, Duran M, Soto JL, Blanco I, Capella G, Valle L (2014) GALNT12 is not a major contributor of familial colorectal cancer type X. Hum Mutat 35: 50-2

 

Valle L (2014) Genetic predisposition to colorectal cancer: where we stand and future perspectives. World J Gastroenterol 20: 9828-49

 

Valle L, Hernandez-Illan E, Bellido F, Aiza G, Castillejo A, Castillejo MI, Navarro M, Segui N, Vargas G, Guarinos C, Juarez M, Sanjuan X, Iglesias S, Alenda C, Egoavil C, Segura A, Juan MJ, Rodriguez-Soler M, Brunet J, Gonzalez S, Jover R, Lazaro C, Capella G, Pineda M, Soto JL, Blanco I (2014) New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis. Hum Mol Genet 23: 3506-12

imatge personal
 

Group leader

Gabriel Capella
Telephone  
+34 932607461
E-mail  
gcapella@idibell.cat
 
© 2015 Institut d'Investigació Biomèdica de Bellvitge



Results by pageInitial date
Select date
TitleFinal date
Select date
Search


Your password is about to expire. Please, write in a new password to continue

Remember this password allows you to access to all IDIBELL’s web applications

New password:
Confirm new password:

Accept



Your password is about to expire. Please, write in a new password to continue

Remember this password allows you to access to all IDIBELL’s web applications

New password:
Confirm new password:

Accept


Cancell

Passwords doesn’t match
The password must have at least 6 characters
The new password can not contain special characters
User register

Name
Surname
Second Surname
E-mail
User
Password
Language


Accept


Cancell




You have not yet answered the Human Resources Strategy for Research survey. It will not take you more than five minutes. Your opinion is very important to improve IDIBELL.

Do you want to complete the survey now?

Yes

No




Further personal and contact information is needed to maintain IDIBELL databases.

Do you wish to fill the form now?

Yes

No